Flexeril Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Other proven treatment options include physical therapy and therapeutic massage. Tramadol’s action on the opioid, serotonin, and norepinephrine receptors has an additive pain-relieving effect and is thus prescribed and dispensed for this indication. The FDA has authorized it for treating moderate to moderately severe pain, such as post-operative discomfort, or chronic conditions like arthritis. If use together is necessary, it is prudent to use the lowest dose and shortest duration necessary to achieve treatment goals. Side effects, such as sedation, respiratory depression, urinary retention, and constipation should be monitoed.

• This case illustrates an example of a toxic overdose with tramadol that resulted in features suggestive of serotonin syndrome.
• Ultram ER should not be given to anyone younger than 18 years old.
• Concurrent administration of acetaminophen/hydrocodone certainly could have been contributory to the presentation.

Toxicology was significant for opioids and negative for benzodiazepines. The table below shows side effects after Flexeril and Ambien administration in recommendable doses. The incidence can be significantly increased if these drugs are overdosed or taken together. This can lead to a drug interaction between Tramadol and cyclobenzaprine, increased sedation, respiratory depression, or other dangerous side effects. No, you should NOT take Tramadol and Flexeril together, unless specifically directed by your doctor.

Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness, drowsiness, and difficulty concentrating.

Are Flexeril and Ultram the Same Thing?

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Chronic use of opioids may cause reduced fertility; it is unknown whether these effects are reversible. A long-acting formulation of cyclobenzaprine has been introduced and is believed by some clinicians to have a lower side effect profile than the immediate-release formulation of this drug. Tramadol is a generic name for an opioid narcotic-like pain reliever that is used for relieving moderate to moderately severe acute and chronic pain.

Some mixtures of medications can lead to serious and even fatal consequences.

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Do not take this drug for more than 3 weeks without talking to your doctor. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. Tramadol is a centrally-acting analgesic indicated for moderate to severe pain.1 It stimulates opioid receptors, and inhibits noradrenaline and serotonin reuptake.

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Cyclobenzaprine is a skeletal muscle relaxant and a depressant of the central nervous system. As a muscle relaxant it is used together with physical therapy and other measures for relaxing muscles and relieving pain and discomfort that can be caused by sprains, strains, and different muscle injuries. You is flexeril sedating should avoid taking tramadol and Flexeril together unless specifically directed by your doctor as the drugs have a potentially significant interaction. In our latest question and answer, our pharmacist discusses whether or not there is a drug interaction between tramadol and Flexeril (cyclobenzaprine).

Dizziness or drowsiness can cause falls, accidents, or severe injuries. It works by blocking the reuptake of the “feel good” neurotransmitters norepinephrine and serotonin that regulate mood. In other words, it can increase serotonin levels in the brain, as well as norepinephrine. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction.

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If a nursing mother is an ultra-rapid metabolizer of tramadol, it could lead to an overdose in the nursing baby and cause very serious side effects. Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

Drug and food interactions

If you notice any other effects, check with your healthcare professional. Both tramadol and Flexeril can provide effective pain relief when used as prescribed by your healthcare provider, but combining these medications should only be done under their supervision. For most patients, the recommended dose of Flexeril is 5 mg three times a day.